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Topic OciChip™


Inflammation OciChip™ (Human / Mouse)

Inflammatory diseases are an inferno of gene expression. To find their causes and to evaluate specific treatments will ultimately require the resolution of time-dependent and stimulus-specific variations in inflammatory gene expression.

Addressing the strong need for simple and reliable tools to follow these coordinated changes, the Microarray Laboratory at Medical School Hanover, Germany, headed by Prof. Michael Kracht, has specifically developed inflammation arrays for mouse and human. Dedicated experts in the field of immune response and inflammation extensively elaborated and validated their content. Working with these Inflammation OciChip™ (Human/Mouse) you can rely on one of the most powerful tools in molecular inflammatory and pharmacogenomical research available today.

Inflammation OciChip™ array is available for human and mouse, and comprises 135 regulated genes most relevant to various inflammatory processes. Selection of genes is based on many years of experience in different inflammatory models as well as an extensive literature search. Much researched data established with these powerfull tools is now accessible online at the CytoBASE Server at the Medical High School Hanover.

Unique Advantages

Gene specific HPSF® oligonucleotide probes
High reproducibility
Extensive quality controls
    - Probes by MALDI-TOF MS
    - Arrays by SYBR® Green
    I staining and random hybridization

Pack includes:

1 Slide
Manual
Hybridization buffer
QC protocol

Reference Data

Series of experiments carried out in the Microarray Laboratory at Medical School, Hanover prove that Inflammation OciChip allows both qualitative and quantitative monitoring of gene expression profiles in human beings and mice. A major part of this array data is now available to the scientific community at this URL: http://www.mh-hannover.de/forschung/sfb566/microarray/index.html

Specifications
Minimal number of genes 136
Information sources NCBI GenBank Release 126
Strand analyzed Sense strand
Number of slides 1
Length of probes 50 mer
Number of oligo-nucleotides per gene 1
Total number of spots 160 in duplicate
Housekeeping genes 19
Spot area 0.8 x 1.45 cm
To Order Inflammation OciChip™ Human Click Here
To Order Inflammation OciChip™ Mouse Click Here



Reference Data
Click here to access CytoBASE Server at Medical School Hanover, Germany

Request Quotation
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Array User Information
Click here to Download Genelists, Manuals, Spotting Pattern and Images
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