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Proteomics

Biotracker™ for Proteomics

Biotracker™ pipelines complex proteomic workflows across projects, experiments, instruments, and can easily interface to downstream analysis tools for searching, imaging analysis and other quantitation tools.

Proteomics is often considered much more complicated than genomics. This is because while an organism’s genome is constant – with exceptions such as the addition of genetic material caused by a virus, or rapid mutations, transpositions, and expansions that can occur in a tumor – the proteome differs from cell to cell. Moreover, even a few samples in a Proteomics Core Lab can generate terabytes of downstream data, therefore, data management is a real issue, often more so than sample management. With this complexity, Biotracker™ pipelines complex proteomic workflows across projects, experiments, instruments (2D gels, mass spectrometers (MALDI-TOFs), LC and GC, Ion Trap, etc. , robotic spot pickers, and scanners), and can easily interface to downstream analysis tools for searching (Mascot™, Sequest™, Protein Prospector™), imaging analysis (GE Healthcare’s DeCyder™ or Bio-Rad’s PDQuest™), and other quantitation tools. Furthermore, Biotracker™ complies with the emerging Proteomics standards such as MIAPE, HUPO Proteomics Standard Initiative, ISB, mzXML and the Protein Standard Initiative’s mzData.

Biotracker™ LIMS can also manage all laboratory resources such as instrument scheduling, personnel, and supplies so you stay in control should you need to reassign resources for urgent work or when instruments go down. In addition, Biotracker™ manages projects internal to your organizations or with collaborators with their contact information. A Proteomics Core’s customers can access their projects, make requests and retrieve results and all associated files through a web interface. In addition, Requestors can upload their samples and experimental design criteria in CSV or Excel formats and Biotracker™ can import these when batch upload makes more sense and is more time effective. Of course, there is role-based security which is completely configurable. Biotracker™ also has a built-in bar code label design capability to support 1 and 2D bar codes with supportable interfaces to the major bar code equipment vendors. Workflows are highly flexible and configurable as the pace of development in Proteomics is always in flux so change control is built-in. Querying has been designed for the SQL challenged so getting the results you want is easy.

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